N-cadherin Mouse mAb
-YM0465
主要信息
Target
N-cadherin
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, FC, ELISA
Conjugate/Modification
Unmodified
货号: YM0465
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; Flow Cyt 1:200-1:400; ELISA 1:10000; Not yet tested in other applications.
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
N-cadherin Monoclonal Antibody detects endogenous levels of N-cadherin protein.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
修饰
Unmodified
克隆性
Monoclonal
克隆号
6H10
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抗原&靶点信息
免疫原:
Purified recombinant fragment of human N-cadherin expressed in E. Coli.
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特异性:
N-cadherin Monoclonal Antibody detects endogenous levels of N-cadherin protein.
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基因名称:
CDH2
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蛋白名称:
Cadherin-2
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别名:
CDH2 ;
CDHN ;
NCAD ;
Cadherin-2 ;
CDw325 ;
Neural cadherin ;
N-cadherin ;
CD antigen CD325
CDHN ;
NCAD ;
Cadherin-2 ;
CDw325 ;
Neural cadherin ;
N-cadherin ;
CD antigen CD325
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背景:
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
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功能:
Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein . Cell membrane, sarcolemma . Cell junction . Cell surface . Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes. .
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组织表达:
研究领域:
>>Cell adhesion molecules ;
>>Arrhythmogenic right ventricular cardiomyopathy
>>Arrhythmogenic right ventricular cardiomyopathy
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文献引用（{{totalcount}}）
货号: YM0465
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
加入购物车
已收藏
收藏
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