CD3 (PN0479) Nb-FC recombinant antibody
-YA0117
主要信息
Target
CD3
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
货号: YA0117
规格
价格
货期
数量
200μg
￥3,780.00
两个月
0
100μg
￥2,300.00
两个月
0
40μg
￥960.00
两个月
0
加入购物车
已收藏
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详细信息
推荐稀释比
ELISA 1:5000-100000
组成
Phosphate-buffered solution
来源
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
特异性
This recombinant monoclonal antibody can detects endogenous levels of CD3 protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度
Please check the information on the tube
修饰
Unmodified
克隆号
PN0479
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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抗原&靶点信息
免疫原:
Purified recombinant Human CD3
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特异性:
This recombinant monoclonal antibody can detects endogenous levels of CD3 protein.
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基因名称:
CD3E T3E
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蛋白名称:
T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
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别名:
T-cell surface glycoprotein CD3 epsilon chain ;
T-cell surface antigen T3/Leu-4 epsilon chain ;
CD antigen CD3e ;
CD3 nanobody ;
T-cell surface antigen T3/Leu-4 epsilon chain ;
CD antigen CD3e ;
CD3 nanobody ;
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背景:
The protein encoded byThis gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects inThis gene cause immunodeficiency.This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
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功能:
The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein .
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组织表达:
Membranous
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信号通路
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Organismal Systems >> Immune system >> T cell receptor signaling pathway
Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation
Organismal Systems >> Immune system >> Th17 cell differentiation
Human Diseases >> Cancer: overview >> PD-L1 expression and PD-1 checkpoint pathway in cancer
Human Diseases >> Immune disease >> Primary immunodeficiency
文献引用（{{totalcount}}）
货号: YA0117
规格
价格
货期
数量
200μg
￥3,780.00
两个月
0
100μg
￥2,300.00
两个月
0
40μg
￥960.00
两个月
0
加入购物车
已收藏
收藏
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