Purified recombinant Human CD73

This recombinant monoclonal antibody can detects endogenous levels of CD73 protein.

NT5E NT5 NTE

5'-nucleotidase (5'-NT) (Ecto-5'-nucleotidase) (CD antigen CD73)

NT5E ;
NT5 ;
NTE ;
5'-nucleotidase ;
5'-NT ;
Ecto-5'-nucleotidase ;
CD antigen CD73 ;
CD73 nanobody ;

The protein encoded byThis gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects inThis gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found forThis gene.[provided by RefSeq, Mar 2011]

Catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,Disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,

Cell membrane ; Lipid-anchor, GPI-anchor .

Leukocyte,Liver,Placenta,Skin