Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CSF3

Granulocyte colony-stimulating factor

CSF3 ;
C17orf33 ;
GCSF ;
Granulocyte colony-stimulating factor ;
G-CSF ;
Pluripoietin ;
Filgrastim ;
Lenograstim

caution:PubMed:2420009 misquotes the gene name as "CSF1".,function:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.,online information:Clinical information on Neupogen/Granulokine,pharmaceutical:Available under the names Neupogen or Granulokine (Amgen/Roche) and Granocyte (Rhone-Poulenc). Used to treat neutropenia (a disorder characterized by an extremely low number of neutrophils in blood).,PTM:O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).,similarity:Belongs to the IL-6 superfamily.,subunit:Monomer.,

immune system development, leukocyte differentiation, myeloid leukocyte differentiation, immune response, positive regulation of cell proliferation, cytokine-mediated signaling pathway, hemopoiesis, myeloid cell differentiation,granulocyte differentiation, regulation of cell proliferation, hemopoietic or lymphoid organ development,

Secreted.