function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. ,similarity:Contains 1 RRM (RNA recognition motif) domain. ,subunit:Self-associates and interacts with EIF3 p170 subunit. ,
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功能:
translation , regulation of translation , regulation of translational initiation , posttranscriptional regulation of gene expression , regulation of cellular protein metabolic process ,