PSCA (PT2119) Mouse mAb
-YM4298
主要信息
Target
PSCA
Host Species
Mouse
Reactivity
Human
Applications
WB, IF, ELISA
MW
13kD (Calculated)
18kD (Observed)
Conjugate/Modification
Unmodified
货号: YM4298
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
This antibody detects endogenous levels of PSCA protein.
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
13kD
实测条带
18kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT2119
同种型
IgG2b,Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human PSCA AA range: 1-100
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特异性:
This antibody detects endogenous levels of PSCA protein.
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基因名称:
PSCA UNQ206/PRO232
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蛋白名称:
Prostate stem cell antigen
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背景:
prostate stem cell antigen(PSCA) Homo sapiens This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
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功能:
May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. ; May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.
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细胞定位:
Cytoplasmic
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文献引用（{{totalcount}}）
货号: YM4298
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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