PSF1 Rabbit pAb
-YN0648
主要信息
Target
PSF1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
21kD (Observed)
Conjugate/Modification
Unmodified
货号: YN0648
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
PSF1 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
21kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein. AA range:1-91
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特异性:
PSF1 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
GINS1 KIAA0186 PSF1
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蛋白名称:
DNA replication complex GINS protein PSF1 (GINS complex subunit 1)
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背景:
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611) , Psf1 , Psf2 (GINS2; MIM 610609) , and Psf3 (GINS3; MIM 610610) . The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al. , 2005 [PubMed 16287864]) .[supplied by OMIM , Mar 2008] ,
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功能:
Function:The GINS complex plays an essential role in the initiation of DNA replication , and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. GINS1 is essential for function. ,induction:Significantly up-regulated in agressive melanomas. ,mass spectrometry:This is the measured mass for the GINS complex PubMed:17557111 ,similarity:Belongs to the GINS1/PSF1 family. ,subunit:Component of the GINS complex which is a heterotetramer of GINS1 , GINS2 , GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro. ,
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细胞定位:
Nucleus . Chromosome . Associates with chromatin. .
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组织表达:
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文献引用（{{totalcount}}）
货号: YN0648
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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