ANX11 Rabbit pAb
-YN0450
主要信息
Target
ANX11
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
55kD (Observed)
Conjugate/Modification
Unmodified
货号: YN0450
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ANX11 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
55kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 280-360
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特异性:
ANX11 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
ANXA11 ANX11
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蛋白名称:
Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)
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背景:
This gene encodes a member of the annexin family , a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains , which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq , Dec 2015] ,
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功能:
Disease:Antibodies against ANXA11 are present in sera from patients with various autoimmune diseases , predominantly in sera from patients with rheumatoid arthritis , systemic lupus erythematosus , or Sjoegren syndrome. ,Domain:A pair of annexin repeats may form one binding site for calcium and phospholipid. ,similarity:Belongs to the annexin family. ,similarity:Contains 4 annexin repeats. ,subcellular location:Found throughout the nucleoplasm at interphase and at the mitotic phase is concentrated at the loop-like structure around the mitotic apparatus (By similarity) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. ,
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细胞定位:
Cytoplasm . Melanosome. Nucleus envelope. Nucleus , nucleoplasm . Cytoplasm , cytoskeleton , spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity) . Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope , with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent. .
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研究领域:
>>Amyotrophic lateral sclerosis
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货号: YN0450
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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