RPB7 Rabbit pAb
-YN0660
主要信息
Target
RPB7
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
18kD (Observed)
Conjugate/Modification
Unmodified
货号: YN0660
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
RPB7 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
18kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein. AA range:19-69
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特异性:
RPB7 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
POLR2G RPB7
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蛋白名称:
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
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背景:
This gene encodes the seventh largest subunit of RNA polymerase II , the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation , and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq , Jan 2009] ,
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功能:
Function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1 , RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity) . Binds RNA. ,similarity:Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. ,subunit:Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits (By similarity) . RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex. ,
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细胞定位:
Nucleus .
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组织表达:
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研究领域:
>>RNA polymerase ;
>>Huntington disease
>>Huntington disease
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文献引用（{{totalcount}}）
货号: YN0660
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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