LONP1 (PT1755R) PT™ Rabbit mAb
-YM9598
主要信息
Target
LONP1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
106kD (Calculated)
106kD (Observed)
Conjugate/Modification
Unmodified
货号: YM9598
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
106kD
实测条带
106kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1755R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
LONP1 PRSS15
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蛋白名称:
LONM
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别名:
Lon protease homolog, mitochondrial ;
LONHs ;
Lon protease-like protein ;
LONP ;
Mitochondrial ATP-dependent protease Lon ;
Serine protease 15 ;
LONHs ;
Lon protease-like protein ;
LONP ;
Mitochondrial ATP-dependent protease Lon ;
Serine protease 15 ;
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背景:
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013],
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功能:
Function:Required for intramitochondrial proteolysis. Catalyzes the initial steps of protein degradation. Hydrolyzes ATP and degrades protein and peptide substrates in an ATP-dependent manner. Binds to single-stranded but not to double-stranded DNA.,similarity:Belongs to the peptidase S16 family.,similarity:Contains 1 Lon domain.,tissue specificity:Duodenum, heart, lung and liver, but not thymus.,
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细胞定位:
Mitochondrion matrix .
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文献引用（{{totalcount}}）
货号: YM9598
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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