Total c-Fms Cell-Based Colorimetric ELISA Kit
-KA3089C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
CSF1R
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别名:
Macrophage colony-stimulating factor 1 receptor ;
CSF-1 receptor ;
CSF-1-R ;
CSF-1R ;
M-CSF-R ;
Proto-oncogene c-Fms ;
CD antigen CD115 ;
CSF-1 receptor ;
CSF-1-R ;
CSF-1R ;
M-CSF-R ;
Proto-oncogene c-Fms ;
CD antigen CD115 ;
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背景:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. ,function:Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains. ,subunit:Interacts with INPPL1/SHIP2 and THOC5. ,tissue specificity:Expressed in bone marrow and in differentiated blood mononuclear cells. ,
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功能:
protein amino acid phosphorylation , phosphorus metabolic process , phosphate metabolic process , cell surface receptor linked signal transduction , enzyme linked receptor protein signaling pathway , transmembrane receptor protein tyrosine kinase signaling pathway , cell proliferation , phosphorylation ,
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细胞定位:
Cell membrane; Single-pass type I membrane protein.
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信号通路
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Organismal Systems >> Development and regeneration >> Osteoclast differentiation
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Cancer: specific types >> Acute myeloid leukemia
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
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