Amino acid:38-478,with human FC tag.

ENTPD1

Ectonucleoside triphosphate diphosphohydrolase 1 (ATP diphosphohydrolase) (ATP-DPH) (ATPDase) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (Nucleoside triphosphate diphosphohydrolase 1) (NTPDase1) (CD antigen CD39)

Ectonucleoside triphosphate diphosphohydrolase 1 ;
ATP diphosphohydrolase ;
ATP-DPH ;
ATPDase ;
Ecto-ATP diphosphohydrolase 1 ;
Ecto-ATPDase 1 ;
Ecto-ATPase 1 ;
Ecto-apyrase ;
Lymphoid cell activation antigen ;
Nucleoside triphosphate diphosphohydrolase 1 ;
NTPDase1 ;
CD antigen CD39 ;
ENTPD1 ;
CD39 ;

Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable) (PubMed:8529670, PubMed:8626624, PubMed:8955160, PubMed:8996251). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow (PubMed:8955160, PubMed:8996251).

Membrane ; Multi-pass membrane protein . Membrane, caveola .

Expressed primarily on activated lymphoid cells (PubMed:7930580). Also expressed in endothelial tissues (PubMed:8955160). Highly expressed in placenta, lung, skeletal muscle, kidney (PubMed:8955160).