Amino acid:60-195,with human FC tag.

KLRG1

Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)

Killer cell lectin-like receptor subfamily G member 1 ;
C-type lectin domain family 15 member A ;
ITIM-containing receptor MAFA-L ;
MAFA-like receptor ;
Mast cell function-associated antigen ;
KLRG1 ;
CLEC15A ;
MAFA ;
MAFAL ;

Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.

Cell membrane ; Single-pass type II membrane protein .

Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.