Total ATF-1 Cell-Based Colorimetric ELISA Kit
-KA3027C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Unmodified
检测方法
Colorimetric
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Total ATF-1 Cell-Based Colorimetric ELISA Kit
KA3027C
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抗原&靶点信息
基因名称:
ATF1
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蛋白名称:
Cyclic AMP-dependent transcription factor ATF-1
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别名:
ATF1 ;
Cyclic AMP-dependent transcription factor ATF-1 ;
cAMP-dependent transcription factor ATF-1 ;
Activating transcription factor 1 ;
Protein TREB36
Cyclic AMP-dependent transcription factor ATF-1 ;
cAMP-dependent transcription factor ATF-1 ;
Activating transcription factor 1 ;
Protein TREB36
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背景:
disease:A chromosomal aberration involving ATF1 is associated with angiomatoid fibrous histiocytoma (AFH) [MIM:612160]. Translocation t (12;16) (q13;p11.2) with FUS generates a chimeric ATF1/FUS protein. ,disease:A chromosomal aberration involving ATF1 is associated with angiomatoid fibrous histiocytoma (AFH) [MIM:612160]. Translocation t (12;22) (q13;q12) with EWSR1 generates a chimeric ATF1/EWSR1 protein. ,function:This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') , a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. ,similarity:Belongs to the bZIP family. ATF subfamily. ,similarity:Contains 1 bZIP domain. ,similarity:Contains 1 KID (kinase-inducible) domain. ,subunit:Binds DNA as a dimer. ,
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功能:
transcription , regulation of transcription , DNA-dependent , regulation of transcription , regulation of RNA metabolic process ,
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细胞定位:
Nucleus .
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信号通路
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