FADD (Phospho Ser191) Cell-Based Colorimetric ELISA Kit
-KA1770C
主要信息
Reactivity
Mouse
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
FADD
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背景:
Q61160 Fas (TNFRSF6) -associated via death domain (Fadd) Mus musculus domain:Contains a death domain involved in the binding of the corresponding domain within Fas receptor. ,function:Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. ,PTM:Phosphorylated. ,similarity:Contains 1 death domain. ,similarity:Contains 1 DED (death effector) domain. ,subunit:Interacts with CFLAR , PEA15 and MBD4. When phosphorylated , part of a complex containing HIPK3 and FAS. May interact with MAVS/IPS1. Interacts with LRDD. ,
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功能:
apoptosis , cell death , regulation of cell death , programmed cell death , death , regulation of apoptosis , regulation of programmed cell death ,
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