Gab2 (Phospho Tyr643) Cell-Based Colorimetric ELISA Kit
-KA1749C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
GAB2
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别名:
GRB2-associated-binding protein 2 ;
GRB2-associated binder 2 ;
Growth factor receptor bound protein 2-associated protein 2 ;
pp100 ;
GRB2-associated binder 2 ;
Growth factor receptor bound protein 2-associated protein 2 ;
pp100 ;
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背景:
PTM:Dephosphorylated by PTPN11. ,PTM:Phosphorylated on tyrosine residue (s) by the thrombopoietin receptor (TPOR) , stem cell factor receptor (SCFR) , and T-cell and B-cell antigen receptors , gp130 , IL-2R and IL-3R. ,similarity:Belongs to the GAB family. ,similarity:Contains 1 PH domain. ,subunit:Interacts with GRB2 , PI-3 kinase and with other SH2-containing proteins. ,
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功能:
cell motion , cell surface receptor linked signal transduction , integrin-mediated signaling pathway , cell migration , cell motility , localization of cell ,
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细胞定位:
Cytoplasm . Cell membrane .
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信号通路
Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway
Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis
Organismal Systems >> Development and regeneration >> Osteoclast differentiation
Human Diseases >> Cancer: specific types >> Chronic myeloid leukemia
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway
Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway
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