Claudin 3 (Phospho Tyr219) Cell-Based Colorimetric ELISA Kit
-KA1743C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
Claudin-3 Rabbit pAb
YT0949
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Primary Antibodies
Claudin-3 (Phospho Tyr219) Rabbit pAb
YP0464
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ELISA Kits
Total Claudin-3 Cell-Based Colorimetric ELISA Kit
KA3217C
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ELISA Kits
Claudin 3 (Phospho Tyr219) Cell-Based Colorimetric ELISA Kit
KA1743C
预览→
抗原&靶点信息
基因名称:
CLDN3
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别名:
Claudin-3 ;
Clostridium perfringens enterotoxin receptor 2 ;
CPE-R 2 ;
CPE-receptor 2 ;
Rat ventral prostate.1 protein homolog ;
hRVP1 ;
Clostridium perfringens enterotoxin receptor 2 ;
CPE-R 2 ;
CPE-receptor 2 ;
Rat ventral prostate.1 protein homolog ;
hRVP1 ;
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背景:
disease:Haploinsufficiency of CLDN3 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS) , a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23. ,function:Plays a major role in tight junction-specific obliteration of the intercellular space , through calcium-independent cell-adhesion activity. ,similarity:Belongs to the claudin family. ,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1 , TJP2/ZO-2 and TJP3/ZO-3. ,
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功能:
response to hypoxia , cell adhesion , cell-cell adhesion , calcium-independent cell-cell adhesion , biological adhesion ,response to oxygen levels ,
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细胞定位:
Cell junction , tight junction . Cell membrane ; Multi-pass membrane protein .
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信号通路
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