详细信息
推荐稀释比
Reconstitute in sterile water for a stock solution
组成
Supplied as solution form in 50mM phosphate pH7.5, 5mM DTT./ Lyophilized from 50mM phosphate pH7.5, 5mM DTT.
来源
E.coli
纯度
>90% as determined by SDS-PAGE
储存
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
抗原&靶点信息
序列:
A DNA sequence encoding the human IL33(Ser112~Thr270) was fused with the N-terminal His Tag
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别名:
C9orf26, IL1F11, NFHEV
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细胞定位:
Nucleus . Chromosome . Cytoplasm . Cytoplasmic vesicle, secretory vesicle . Secreted . Associates with heterochromatin and mitotic chromosomes (PubMed:17185418). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
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组织表达:
Expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. Almost undetectable in placenta.
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信号通路
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