详细信息
推荐稀释比
Reconstitute in sterile water for a stock solution
组成
Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.
来源
Mammalian cells
纯度
>90% as determined by SDS-PAGE
储存
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
抗原&靶点信息
序列:
A DNA sequence encoding the human KIT(Met1-IIe516) was fused with the C-terminal His Tag
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别名:
KIT
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细胞定位:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cytoplasm . Detected in the cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head. .
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组织表达:
[Isoform 3]: In testis, detected in spermatogonia in the basal layer and in interstitial Leydig cells but not in Sertoli cells or spermatocytes inside the seminiferous tubules (at protein level) (PubMed:20601678). Expression is maintained in ejaculated spermatozoa (at protein level) (PubMed:20601678).
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信号通路
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> Central carbon metabolism in cancer
Human Diseases >> Cancer: specific types >> Acute myeloid leukemia
Human Diseases >> Cancer: specific types >> Breast cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
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