SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit
-KA1535C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
SNAI 1 Rabbit pAb
YT4351
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Primary Antibodies
SNAI 1 (Phospho Ser246) Rabbit pAb
YP0568
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ELISA Kits
Total SNAI 1 Cell-Based Colorimetric ELISA Kit
KA4285C
预览→
ELISA Kits
SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit
KA1535C
预览→
抗原&靶点信息
基因名称:
SNAI1
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别名:
Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna ;
Protein snail homolog 1 ;
Protein sna ;
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背景:
snail family transcriptional repressor 1 (SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein , and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq , Jul 2008] ,
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功能:
Function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. ,similarity:Belongs to the snail C2H2-type zinc-finger protein family. ,similarity:Contains 4 C2H2-type zinc fingers. ,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney. ,
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细胞定位:
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107 , Ser-111 , Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
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