Casein Kinase Iα (Phospho Tyr321) Cell-Based Colorimetric ELISA Kit
-KA1528C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
Casein Kinase Iα Rabbit pAb
YT0645
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Primary Antibodies
Casein Kinase Iα (Phospho Thr321) Rabbit pAb
YP0392
预览→
ELISA Kits
Total Casein Kinase Iα Cell-Based Colorimetric ELISA Kit
KA3615C
预览→
ELISA Kits
Casein Kinase Iα (Phospho Tyr321) Cell-Based Colorimetric ELISA Kit
KA1528C
预览→
抗原&靶点信息
基因名称:
CSNK1A1
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别名:
Casein kinase I isoform alpha ;
CKI-alpha ;
CK1 ;
CKI-alpha ;
CK1 ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein. ,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'. ,similarity:Belongs to the protein kinase superfamily. ,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. ,similarity:Contains 1 protein kinase domain. ,subunit:Monomer. Interacts with the Axin complex. ,
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功能:
protein amino acid phosphorylation , phosphorus metabolic process , phosphate metabolic process , cell surface receptor linked signal transduction , Wnt receptor signaling pathway , phosphorylation ,
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细胞定位:
Cytoplasm . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome . Chromosome , centromere , kinetochore . Nucleus speckle . Cytoplasm , cytoskeleton , cilium basal body . Cytoplasm , cytoskeleton , spindle . Localizes to the centrosome in interphase cells , and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688) . .
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信号通路
Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma
Human Diseases >> Cancer: specific types >> Gastric cancer
Human Diseases >> Cancer: specific types >> Breast cancer
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Environmental Information Processing >> Signal transduction >> Hedgehog signaling pathway
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