SSB (Phospho Ser366) Cell-Based Colorimetric ELISA Kit
-KA1523C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
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SSB (Phospho Ser366) Cell-Based Colorimetric ELISA Kit
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抗原&靶点信息
基因名称:
SSB
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别名:
Lupus La protein ;
La autoantigen ;
La ribonucleoprotein ;
Sjoegren syndrome type B antigen ;
SS-B ;
La autoantigen ;
La ribonucleoprotein ;
Sjoegren syndrome type B antigen ;
SS-B ;
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背景:
disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign. ,function:La protein plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S , 5S , 7S , and 7-2 RNAs. ,PTM:Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein. ,PTM:The N-terminus is blocked. ,similarity:Contains 1 HTH La-type RNA-binding domain. ,similarity:Contains 1 RRM (RNA recognition motif) domain. ,subunit:Interacts with DDX15. May interact with RUFY1. ,
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功能:
RNA processing , tRNA metabolic process , tRNA modification , tRNA processing , histone mRNA metabolic process , RNA modification , mRNA metabolic process , ncRNA processing , ncRNA metabolic process ,
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细胞定位:
Nucleus .
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