Recombinant SARS-CoV-2(Covid-19) NSP10
-YD2188
主要信息
Reactivity
Humanvirus
Applications
ELISA, ECL, Immunogold,
MW
17.99kDa (Calculated)
18kDa (Observed)
详细信息
推荐稀释比
Testing in progress
来源
E.coli
纯度
>90% as determined by SDS-PAGE
储存
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
理论分子量
17.99kDa
实测条带
18kDa
抗原&靶点信息
基因名称:
ORF1ab
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蛋白名称:
nsp10,GFL
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数据库链接:
| Organism | 基因 ID | SwissProt |
|---|---|---|
| Human | YP_009725306.1; |
背景:
Recombinant SARS-CoV-2 NSP10 is produced by E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with N-His Tag
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功能:
Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.
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研究领域:
For research use only .Not for use in clinical diagnostic procedures.
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