详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS
来源
E.coli
纯度
SDS-PAGE >90%
储存
-20°C/6 month,-80°C for long storage
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
序列:
Amino acid: 40-279, with his-MBP tag.
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基因名称:
NRF1
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蛋白名称:
Nrf1 protein
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别名:
Nuclear respiratory factor 1 ;
NRF-1 ;
Alpha palindromic-binding protein ;
Alpha-pal ;
NRF-1 ;
Alpha palindromic-binding protein ;
Alpha-pal ;
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背景:
function:Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.,PTM:Phosphorylation enhances DNA binding.,similarity:Belongs to the NRF1/Ewg family.,subunit:Homodimer. Binds DNA as a dimer. Interacts with PPRC1.,tissue specificity:Ubiquitously expressed with strongest expression in skeletal muscle.,
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功能:
generation of precursor metabolites and energy, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, mitochondrion organization, regulation of transcription, regulation of RNA metabolic process,
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细胞定位:
Nucleus.
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组织表达:
Ubiquitously expressed with strongest expression in skeletal muscle.
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信号通路
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