Calnexin protein
-YD0118
主要信息
Reactivity
Human
Applications
WB, SDS-PAGE
详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS
来源
E.coli
纯度
SDS-PAGE >90%
储存
-20°C/6 month,-80°C for long storage
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
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Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
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抗原&靶点信息
序列:
Amino acid: 19-236, with his-MBP tag.
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基因名称:
CANX
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蛋白名称:
Calnexin protein
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别名:
Calnexin ;
IP90 ;
Major histocompatibility complex class I antigen-binding protein p88 ;
p90 ;
IP90 ;
Major histocompatibility complex class I antigen-binding protein p88 ;
p90 ;
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背景:
function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
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功能:
protein folding, protein localization, protein secretion, protein transport, secretion by cell, establishment of protein localization, secretion,
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细胞定位:
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
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