KIF11/Eg5 (Phospho Thr926) Cell-Based Colorimetric ELISA Kit
-KA1502C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
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Eg5 Rabbit pAb
YT1480
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Primary Antibodies
Eg5 (Phospho Thr926) Rabbit pAb
YP0372
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ELISA Kits
Total KIF11/Eg5 Cell-Based Colorimetric ELISA Kit
KA4153C
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ELISA Kits
KIF11/Eg5 (Phospho Thr926) Cell-Based Colorimetric ELISA Kit
KA1502C
预览→
抗原&靶点信息
基因名称:
KIF11
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别名:
Kinesin-like protein KIF11 ;
Kinesin-like protein 1 ;
Kinesin-like spindle protein HKSP ;
Kinesin-related motor protein Eg5 ;
Thyroid receptor-interacting protein 5 ;
TR-interacting protein 5 ;
TRIP-5 ;
Kinesin-like protein 1 ;
Kinesin-like spindle protein HKSP ;
Kinesin-related motor protein Eg5 ;
Thyroid receptor-interacting protein 5 ;
TR-interacting protein 5 ;
TRIP-5 ;
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背景:
function:Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays. ,PTM:Phosphorylated exclusively on serine during S phase , but on both serine and Thr-926 during mitosis , so controlling the association of KIF11 with the spindle apparatus (probably during early prophase) . Phosphorylated upon DNA damage , probably by ATM or ATR. ,similarity:Belongs to the kinesin-like protein family. BimC subfamily. ,similarity:Contains 1 kinesin-motor domain. ,subunit:Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Component of a large chromatin remodeling complex , at least composed of MYSM1 , PCAF , RBM10 and KIF11/TRIP5. ,
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功能:
M phase of mitotic cell cycle , microtubule cytoskeleton organization , mitotic cell cycle , M phase , nuclear division ,cytoskeleton organization , microtubule-based process , microtubule-based movement , cell cycle , spindle organization ,mitotic spindle organization , mitosis , centrosome cycle , mitotic centrosome separation , cell cycle process , cell cycle phase , microtubule organizing center organization , organelle fission , centrosome organization , centrosome separation , spindle pole body organization , cell division ,
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细胞定位:
Cytoplasm . Cytoplasm , cytoskeleton , spindle pole .
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