IL-2Rβ (Phospho Tyr364) Cell-Based Colorimetric ELISA Kit
-KA1496C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
IL-2Rβ Rabbit pAb
YT2331
预览→
Primary Antibodies
IL-2Rβ (Phospho Tyr364) Rabbit pAb
YP0370
预览→
Primary Antibodies
IL-2Rβ (Phospho Tyr364) Rabbit pAb
YP0369
预览→
ELISA Kits
Total IL-2Rβ Cell-Based Colorimetric ELISA Kit
KA4135C
预览→
ELISA Kits
IL-2Rβ (Phospho Tyr364) Cell-Based Colorimetric ELISA Kit
KA1496C
预览→
抗原&靶点信息
基因名称:
IL2RB
展开内容
别名:
IL2RB ;
Interleukin-2 receptor subunit beta ;
IL-2 receptor subunit beta ;
IL-2R subunit beta ;
IL-2RB ;
High affinity IL-2 receptor subunit beta ;
p70-75 ;
p75 ;
CD antigen CD122
Interleukin-2 receptor subunit beta ;
IL-2 receptor subunit beta ;
IL-2R subunit beta ;
IL-2RB ;
High affinity IL-2 receptor subunit beta ;
p70-75 ;
p75 ;
CD antigen CD122
展开内容
背景:
domain:The box 1 motif is required for JAK interaction and/or activation. ,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. ,function:Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. ,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily. ,similarity:Contains 1 fibronectin type-III domain. ,subunit:Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer , an intermediate affinity monomer (beta chain) , and a low affinity monomer (alpha chain) . The high and intermediate affinity forms also associate with a gamma chain. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I. ,
展开内容
功能:
protein complex assembly , anti-apoptosis , positive regulation of macromolecule metabolic process , positive regulation of gene expression , regulation of cell death , cytokine-mediated signaling pathway , regulation of apoptosis , negative regulation of apoptosis , regulation of programmed cell death , negative regulation of programmed cell death ,macromolecular complex subunit organization , regulation of survival gene product expression , positive regulation of survival gene product expression , negative regulation of cell death , macromolecular complex assembly , protein complex biogenesis ,
展开内容
细胞定位:
Cell membrane ; Single-pass type I membrane protein .
展开内容
信号通路
Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation
Organismal Systems >> Immune system >> Th17 cell differentiation
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
文献引用（{{totalcount}}）
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}