function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . ICAM3 is also a ligand for integrin alpha-D/beta-2. ,online information:ICAM-3 ,PTM:N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains. ,PTM:Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. ,similarity:Belongs to the immunoglobulin superfamily. ICAM family. ,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains. ,
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