PKD2 (Phospho Ser876) Cell-Based Colorimetric ELISA Kit
-KA1415C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
PKD2 Rabbit pAb
YT3773
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Primary Antibodies
PKD2 (Phospho Ser876) Rabbit pAb
YP0341
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ELISA Kits
Total PKD2 Cell-Based Colorimetric ELISA Kit
KA4244C
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ELISA Kits
PKD2 (Phospho Ser876) Cell-Based Colorimetric ELISA Kit
KA1415C
预览→
抗原&靶点信息
基因名称:
PRKD2
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别名:
Serine/threonine-protein kinase D2 ;
nPKC-D2 ;
nPKC-D2 ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein. ,enzyme regulation:Activated by diacylglycerol and phorbol esters. ,function:Calcium-independent , phospholipid-dependent , serine- and threonine-specific protein kinase. ,PTM:Autophosphorylated. Phorbol esters stimulates autophosphorylation. Phosphorylation of Ser-876 correlates with the activation status of the kinase. ,similarity:Belongs to the protein kinase superfamily. ,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily. ,similarity:Contains 1 PH domain. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers. ,tissue specificity:Widely expressed. ,
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功能:
protein amino acid phosphorylation , phosphorus metabolic process , phosphate metabolic process , intracellular signaling cascade , phosphorylation ,
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细胞定位:
Cytoplasm . Cell membrane . Nucleus . Golgi apparatus , trans-Golgi network . Translocation to the cell membrane is required for kinase activation. Accumulates in the nucleus upon CK1-mediated phosphorylation after activation of G-protein-coupled receptors. Nuclear accumulation is regulated by blocking nuclear export of active PRKD2 rather than by increasing import. .
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组织表达:
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信号通路
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