A-RAF (Phospho Tyr302) Cell-Based Colorimetric ELISA Kit
-KA1397C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
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ELISA Kits
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抗原&靶点信息
基因名称:
ARAF
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别名:
Serine/threonine-protein kinase A-Raf ;
Proto-oncogene A-Raf ;
Proto-oncogene A-Raf-1 ;
Proto-oncogene Pks ;
Proto-oncogene A-Raf ;
Proto-oncogene A-Raf-1 ;
Proto-oncogene Pks ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein. ,cofactor:Binds 2 zinc ions per subunit. ,function:Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. ,similarity:Belongs to the protein kinase superfamily. ,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. ,similarity:Contains 1 phorbol-ester/DAG-type zinc finger. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 1 RBD (Ras-binding) domain. ,subunit:Interacts with TH1L/NELFD. ,tissue specificity:Predominantly in urogenital tissues. ,
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功能:
protein amino acid phosphorylation , phosphorus metabolic process , phosphate metabolic process , intracellular signaling cascade , phosphorylation ,
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组织表达:
信号通路
Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton
Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity
Organismal Systems >> Endocrine system >> Insulin signaling pathway
Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: specific types >> Colorectal cancer
Human Diseases >> Cancer: specific types >> Pancreatic cancer
Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma
Human Diseases >> Cancer: specific types >> Gastric cancer
Human Diseases >> Cancer: specific types >> Glioma
Human Diseases >> Cancer: specific types >> Acute myeloid leukemia
Human Diseases >> Cancer: specific types >> Chronic myeloid leukemia
Human Diseases >> Cancer: specific types >> Melanoma
Human Diseases >> Cancer: specific types >> Renal cell carcinoma
Human Diseases >> Cancer: specific types >> Bladder cancer
Human Diseases >> Cancer: specific types >> Prostate cancer
Human Diseases >> Cancer: specific types >> Endometrial cancer
Human Diseases >> Cancer: specific types >> Breast cancer
Human Diseases >> Cancer: specific types >> Non-small cell lung cancer
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> ErbB signaling pathway
Environmental Information Processing >> Signal transduction >> FoxO signaling pathway
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