PLCβ3 (Phospho Ser537) Cell-Based Colorimetric ELISA Kit
-KA1390C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
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ELISA Kits
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抗原&靶点信息
基因名称:
PLCB3
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别名:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 ;
Phosphoinositide phospholipase C-beta-3 ;
Phospholipase C-beta-3 ;
PLC-beta-3 ;
Phosphoinositide phospholipase C-beta-3 ;
Phospholipase C-beta-3 ;
PLC-beta-3 ;
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背景:
catalytic activity:1-phosphatidyl-1D-myo-inositol 4 ,5-bisphosphate + H (2) O = 1D-myo-inositol 1 ,4 ,5-trisphosphate + diacylglycerol. ,cofactor:Calcium. ,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1 ,4 ,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. ,similarity:Contains 1 C2 domain. ,similarity:Contains 1 PI-PLC X-box domain. ,similarity:Contains 1 PI-PLC Y-box domain. ,subunit:Interacts with SHANK2 (By similarity) . Interacts with LPAR2. ,
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功能:
phospholipid metabolic process , intracellular signaling cascade , phospholipid catabolic process , lipid catabolic process ,organophosphate metabolic process , cellular lipid catabolic process ,
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细胞定位:
Cytoplasm . Membrane . Nucleus . And particulate fractions. .
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信号通路
Cellular Processes >> Cellular community - eukaryotes >> Gap junction
Organismal Systems >> Immune system >> Platelet activation
Organismal Systems >> Immune system >> Neutrophil extracellular trap formation
Organismal Systems >> Immune system >> NOD-like receptor signaling pathway
Organismal Systems >> Immune system >> Chemokine signaling pathway
Organismal Systems >> Endocrine system >> Insulin secretion
Organismal Systems >> Endocrine system >> Glucagon signaling pathway
Organismal Systems >> Endocrine system >> GnRH signaling pathway
Organismal Systems >> Endocrine system >> Estrogen signaling pathway
Organismal Systems >> Endocrine system >> Oxytocin signaling pathway
Organismal Systems >> Endocrine system >> Relaxin signaling pathway
Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion
Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes
Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Organismal Systems >> Nervous system >> Glutamatergic synapse
Organismal Systems >> Nervous system >> Cholinergic synapse
Organismal Systems >> Nervous system >> Dopaminergic synapse
Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Neurodegenerative disease >> Alzheimer disease
Human Diseases >> Neurodegenerative disease >> Huntington disease
Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Environmental Information Processing >> Signal transduction >> Apelin signaling pathway
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway
Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
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