PBK/TOPK (Phospho Thr9) Cell-Based Colorimetric ELISA Kit
-KA1382C
主要信息
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
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Primary Antibodies
PBK (Phospho Thr9) Rabbit pAb
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ELISA Kits
Total PBK/TOPK Cell-Based Colorimetric ELISA Kit
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ELISA Kits
PBK/TOPK (Phospho Thr9) Cell-Based Colorimetric ELISA Kit
KA1382C
预览→
抗原&靶点信息
基因名称:
PBK
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别名:
Lymphokine-activated killer T-cell-originated protein kinase ;
Cancer/testis antigen 84 ;
CT84 ;
MAPKK-like protein kinase ;
Nori-3 ;
PDZ-binding kinase ;
Spermatogenesis-related protein kinase ;
SPK ;
T-LAK cell-originated protein kinase ;
Cancer/testis antigen 84 ;
CT84 ;
MAPKK-like protein kinase ;
Nori-3 ;
PDZ-binding kinase ;
Spermatogenesis-related protein kinase ;
SPK ;
T-LAK cell-originated protein kinase ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein. ,enzyme regulation:Activated by phosphorylation. ,function:Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated , forms a complex with TP53 , leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. ,PTM:Phosphorylated; in a cell-cycle dependent manner at mitosis. ,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase kinase subfamily. ,similarity:Contains 1 protein kinase domain. ,subunit:Interacts with DLG1 and TP53. ,tissue specificity:Expressed in the testis and placenta. In the testis , restrictedly expressed in outer cell layer of seminiferous tubules. ,
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功能:
M phase of mitotic cell cycle , mitotic cell cycle , M phase , nuclear division , protein amino acid phosphorylation ,phosphorus metabolic process , phosphate metabolic process , cell cycle , mitosis , phosphorylation , cell cycle process ,cell cycle phase , organelle fission ,
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