Total K6PP Cell-Based Colorimetric ELISA Kit
-KA4344C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
K6PP
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别名:
6-phosphofructokinase type C ;
6-phosphofructokinase, platelet type ;
Phosphofructo-1-kinase isozyme C ;
PFK-C ;
Phosphofructokinase 1 ;
Phosphohexokinase ;
6-phosphofructokinase, platelet type ;
Phosphofructo-1-kinase isozyme C ;
PFK-C ;
Phosphofructokinase 1 ;
Phosphohexokinase ;
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背景:
catalytic activity:ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.,cofactor:Magnesium.,enzyme regulation:Allosteric enzyme activated by ADP, AMP, or fructose bisphosphate and inhibited by ATP or citrate.,miscellaneous:In human PFK exists as a system of 3 types of subunits, PFKM (muscle), PFKL (liver) and PFKP (platelet) isoenzymes.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.,similarity:Belongs to the phosphofructokinase family. Two domains subfamily.,subunit:Tetramer. Muscle is M4, liver is L4, and red cell is M3L, M2L2, or ML3. A subunit composition with a higher proportion of platelet type subunits is found in platelets, brain and fibroblasts.,
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功能:
monosaccharide metabolic process, fructose metabolic process, fructose 6-phosphate metabolic process, glucose metabolic process, glucose catabolic process, generation of precursor metabolites and energy, glycolysis, protein complex assembly, carbohydrate catabolic process, hexose metabolic process, hexose catabolic process, fructose 1,6-bisphosphate metabolic process, macromolecular complex subunit organization, cellular carbohydrate catabolic process, alcohol catabolic process, monosaccharide catabolic process, protein oligomerization, protein homooligomerization, protein tetramerization, protein homotetramerization, macromolecular complex assembly,protein complex biogenesis,
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细胞定位:
Cytoplasm .
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信号通路
Organismal Systems >> Endocrine system >> Glucagon signaling pathway
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Human Diseases >> Cancer: overview >> Central carbon metabolism in cancer
Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway
Environmental Information Processing >> Signal transduction >> AMPK signaling pathway
Genetic Information Processing >> Folding, sorting and degradation >> RNA degradation
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