LIMK1

LIM domain kinase 1 ;
LIMK-1 ;

regulation of cell growth, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cytoskeleton organization, intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, Rho protein signal transduction, regulation of cell size, positive regulation of cell development, regulation of cell morphogenesis involved in differentiation, regulation of neuron projection development, phosphorylation, regulation of cell morphogenesis, actin filament-based process, actin cytoskeleton organization, positive regulation of cell growth, regulation of axon extension, regulation of cell projection organization,positive regulation of cell projection organization, regulation of cellular component size, regulation of growth, positive regulation of cell differentiation, regulation of neuron differentiation, positive regulation of axon extension, positive regulation of cell size, positive regulation of growth, regulation of developmental growth, positive regulation of developmental growth, regulation of neurogenesis, positive regulation of neurogenesis, regulation of axonogenesis,positive regulation of axonogenesis, positive regulation of developmental process, positive regulation of cellular component organization, regulation of nervous system development, regulation of cell development,

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton . Cell projection, lamellipodium . Predominantly found in the cytoplasm. Localizes in the lamellipodium in a CDC42BPA, CDC42BPB and FAM89B/LRAP25-dependent manner. .

Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.