Total XRCC1 Cell-Based Colorimetric ELISA Kit
-KA4327C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
XRCC1 Rabbit pAb
YT4917
预览→
Primary Antibodies
XRCC1 Mouse mAb
YM1417
预览→
ELISA Kits
Total XRCC1 Cell-Based Colorimetric ELISA Kit
KA4327C
预览→
ELISA Kits
Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
KE1372
预览→
ELISA Kits
Human RNASE3/ECP(Ribonuclease A3/Eosinophil Cationic Protein) ELISA Kit
KE1709
预览→
抗原&靶点信息
基因名称:
XRCC1
展开内容
别名:
DNA repair protein XRCC1 ;
X-ray repair cross-complementing protein 1 ;
X-ray repair cross-complementing protein 1 ;
展开内容
背景:
function:Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.,polymorphism:Carriers of the polymorphic Gln-399 allele may be at greater risk for tobacco- and age-related DNA damage.,PTM:Phosphorylation of Ser-371 causes dimer dissociation. Phosphorylation by CK2 promotes interaction with APTX and APLF.,PTM:Sumoylated.,similarity:Contains 2 BRCT domains.,subcellular location:Accumulates at sites of DNA damage.,subunit:Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF.,
展开内容
功能:
single strand break repair, response to hypoxia, DNA metabolic process, DNA repair, response to DNA damage stimulus, response to organic substance, cellular response to stress, response to drug, response to oxygen levels,
展开内容
细胞定位:
Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
展开内容
组织表达:
Expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells (at protein level).
展开内容
文献引用（{{totalcount}}）
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}