IL-3Rβ (Phospho Tyr593) Cell-Based Colorimetric ELISA Kit
-KA1261C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
Primary Antibodies
IL-3Rβ Rabbit pAb
YT2333
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Primary Antibodies
IL-3Rβ (Phospho Tyr593) Rabbit pAb
YP0639
预览→
ELISA Kits
Total IL-3Rβ Cell-Based Colorimetric ELISA Kit
KA4136C
预览→
ELISA Kits
IL-3Rβ (Phospho Tyr593) Cell-Based Colorimetric ELISA Kit
KA1261C
预览→
抗原&靶点信息
基因名称:
CSF2RB IL3RB IL5RB
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别名:
CSF2RB ;
IL3RB ;
IL5RB ;
Cytokine receptor common subunit beta ;
CDw131 ;
GM-CSF/IL-3/IL-5 receptor common beta subunit ;
CD antigen CD131
IL3RB ;
IL5RB ;
Cytokine receptor common subunit beta ;
CDw131 ;
GM-CSF/IL-3/IL-5 receptor common beta subunit ;
CD antigen CD131
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背景:
disease:Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. ,domain:The box 1 motif is required for JAK interaction and/or activation. ,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. ,function:High affinity receptor for interleukin-3 , interleukin-5 and granulocyte-macrophage colony-stimulating factor. ,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily. ,similarity:Contains 2 fibronectin type-III domains. ,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3 , IL5 and GM-CSF receptors. ,
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功能:
respiratory gaseous exchange , cytokine-mediated signaling pathway ,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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信号通路
Cellular Processes >> Cell growth and death >> Apoptosis
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
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