Total VE-Cadherin Cell-Based Colorimetric ELISA Kit
-KA4320C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
CDH5
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别名:
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144 ;
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背景:
function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.,similarity:Contains 5 cadherin domains.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,tissue specificity:Endothelial tissues and brain.,
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功能:
blood vessel development, vasculature development, blood vessel maturation, cell adhesion, homophilic cell adhesion,negative regulation of cell proliferation, cell-cell adhesion, developmental maturation, biological adhesion, regulation of cell proliferation,
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细胞定位:
Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. .
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组织表达:
Endothelial tissues and brain.
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信号通路
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