CD19 (Phospho Tyr531) Cell-Based Colorimetric ELISA Kit
-KA1238C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Phospho
详细信息
储存
2-8°C/6 months,Ship by ice bag
修饰
Phospho
检测方法
Colorimetric
相关产品
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CD19 (Phospho Tyr531) Rabbit pAb
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ELISA Kits
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ELISA Kits
CD19 (Phospho Tyr531) Cell-Based Colorimetric ELISA Kit
KA1238C
预览→
抗原&靶点信息
基因名称:
CD19
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别名:
B-lymphocyte antigen CD19 ;
B-lymphocyte surface antigen B4 ;
Differentiation antigen CD19 ;
T-cell surface antigen Leu-12 ;
CD antigen CD19 ;
B-lymphocyte surface antigen B4 ;
Differentiation antigen CD19 ;
T-cell surface antigen Leu-12 ;
CD antigen CD19 ;
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背景:
disease:Defects in CD19 are a cause of hypogammaglobulinemia [MIM:107265]. ,function:Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. ,online information:CD19 mutation db ,PTM:Phosphorylated on serine and threonine upon DNA damage , probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. ,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains. ,subunit:Forms a complex with CD21 , CD81 and CD225 in the membrane of mature B cells. Interacts with VAV. Interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. Interacts with PLCG2 when phosphorylated on Tyr-409. ,
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功能:
activation of immune response , immune response-activating cell surface receptor signaling pathway , positive regulation of immune system process , immune response-activating signal transduction , immune response-regulating signal transduction , immune response-regulating cell surface receptor signaling pathway , defense response , cellular defense response , cell surface receptor linked signal transduction , positive regulation of response to stimulus , positive regulation of immune response , antigen receptor-mediated signaling pathway , B cell receptor signaling pathway ,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .
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信号通路
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