SRF

Serum response factor ;
SRF ;

function:SRF is a transcription factor that binds to the serum response element (SRE) , a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) . Required for cardiac differentation and maturation. ,PTM:Phosphorylated by PRKDC. ,similarity:Contains 1 MADS-box domain. ,subunit:Binds DNA as a multimer , probably a dimer. Interacts with MLLT7/FOXO4 , NKX3A and SSRP1. Interacts with ARID2 and SRFBP1 (By similarity) . Forms complexes with ARID2 , MYOCD , NKX2-5 and SRFBP1. ,

angiogenesis , blood vessel development , in utero embryonic development , blastocyst development , blastocyst formation , trophectodermal cell differentiation , vasculature development , heart looping , sprouting angiogenesis , cell migration during sprouting angiogenesis , heart morphogenesis , transcription , regulation of transcription , DNA-dependent , regulation of transcription from RNA polymerase II promoter , cell motion , regulation of muscle contraction ,regulation of smooth muscle contraction , heart development , aging , response to wounding , response to toxin ,response to endogenous stimulus , response to hormone stimulus , embryonic development ending in birth or egg hatching , positive regulation of biosynthetic process , response to organic substance , senescence , regulation of specific transcription from RNA polymerase II promoter , positive regulation of specific transcription from RNA polymerase II promoter , positive regulation of macromolecule biosynthetic process , positive regulation of macromolecule metabolic process , positive regulation of gene expression , positive regulation of transcription via serum response element binding , cell migration , cellular homeostasis , neuron differentiation , positive regulation of cellular biosynthetic process , positive regulation of protein complex assembly , regulation of gene-specific transcription ,response to cytokine stimulus , tube morphogenesis , tube development , wound healing , homeostatic process ,chordate embryonic development , positive regulation of gene-specific transcription , regulation of protein complex assembly , blood vessel endothelial cell migration , endothelial cell migration , regulation of system process , regulation of cellular component biogenesis , regulation of transcription , positive regulation of cell differentiation , positive regulation of transcription , DNA-dependent , positive regulation of muscle contraction , positive regulation of nucleobase , nucleoside , nucleotide and nucleic acid metabolic process , positive regulation of transcription , positive regulation of transcription from RNA polymerase II promoter , positive regulation of smooth muscle contraction , muscle maintenance , blood vessel morphogenesis , neuron development , cell motility , positive regulation of developmental process , positive regulation of cellular component organization , regulation of muscle cell differentiation , regulation of smooth muscle cell differentiation , positive regulation of nitrogen compound metabolic process , positive regulation of multicellular organismal process , regulation of RNA metabolic process , positive regulation of RNA metabolic process ,localization of cell , angiogenesis involved in wound healing , anatomical structure homeostasis , regulation of transcription initiation from RNA polymerase II promoter , positive regulation of transcription initiation from RNA polymerase II promoter ,

Nucleus .