Total SNAI 1 Cell-Based Colorimetric ELISA Kit
-KA4285C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
SNAI 1 Rabbit pAb
YT4351
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Primary Antibodies
SNAI 1 (Phospho Ser246) Rabbit pAb
YP0568
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ELISA Kits
Total SNAI 1 Cell-Based Colorimetric ELISA Kit
KA4285C
预览→
ELISA Kits
SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit
KA1535C
预览→
抗原&靶点信息
基因名称:
SNAI1
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蛋白名称:
Zinc finger protein SNAI1(snail)
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别名:
Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna ;
Protein snail homolog 1 ;
Protein sna ;
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背景:
snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
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功能:
Function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,
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细胞定位:
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
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组织表达:
Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
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