Total PKD2 Cell-Based Colorimetric ELISA Kit
-KA4244C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
PKD2 Rabbit pAb
YT3773
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Primary Antibodies
PKD2 (Phospho Ser876) Rabbit pAb
YP0341
预览→
ELISA Kits
Total PKD2 Cell-Based Colorimetric ELISA Kit
KA4244C
预览→
ELISA Kits
PKD2 (Phospho Ser876) Cell-Based Colorimetric ELISA Kit
KA1415C
预览→
抗原&靶点信息
基因名称:
PRKD2
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别名:
Serine/threonine-protein kinase D2 ;
nPKC-D2 ;
nPKC-D2 ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by diacylglycerol and phorbol esters.,function:Calcium-independent, phospholipid-dependent, serine- and threonine-specific protein kinase.,PTM:Autophosphorylated. Phorbol esters stimulates autophosphorylation. Phosphorylation of Ser-876 correlates with the activation status of the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,tissue specificity:Widely expressed.,
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功能:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, phosphorylation,
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细胞定位:
Cytoplasm . Cell membrane . Nucleus . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation. Accumulates in the nucleus upon CK1-mediated phosphorylation after activation of G-protein-coupled receptors. Nuclear accumulation is regulated by blocking nuclear export of active PRKD2 rather than by increasing import. .
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组织表达:
Widely expressed.
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信号通路
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