GRM2

function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.,similarity:Belongs to the G-protein coupled receptor 3 family.,subunit:Interacts with GRASP.,tissue specificity:Widely expressed in different regions of the adult brain as well as in fetal brain.,

regulation of neurotransmitter levels, generation of a signal involved in cell-cell signaling, regulation of nucleotide metabolic process, neurotransmitter transport, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, negative regulation of adenylate cyclase activity, cell-cell signaling, synaptic transmission, neurotransmitter secretion, behavior, locomotory behavior, adult locomotory behavior, response to organic substance, glutamate secretion, response to organic cyclic substance, response to tropane, transmission of nerve impulse, adult behavior, regulation of cyclic nucleotide metabolic process, regulation of cyclic nucleotide biosynthetic process, regulation of nucleotide biosynthetic process, regulation of cAMP metabolic process, regulation of cAMP biosynthetic process, regulation of cyclase activity, negative regulation of cyclase activity, secretion by cell,response to cocaine, negative regulation of catalytic activity, response to alkaloid, negative regulation of molecular function, regulation of adenylate cyclase activity, secretion, behavioral response to cocaine, neurological system process, regulation of lyase activity, negative regulation of lyase activity,

Cell membrane; Multi-pass membrane protein. Cell junction, synapse . Cell projection, dendrite .

Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.