IL2RA

Interleukin-2 receptor subunit alpha ;
IL-2 receptor subunit alpha ;
IL-2-RA ;
IL-2R subunit alpha ;
IL2-RA ;
TAC antigen ;
p55 ;
CD antigen CD25 ;

disease:Genetic variations in IL2RA are associated with susceptibility to insulin-dependent diabetes mellitus type 10 (IDDM10) [MIM:601942].,function:Receptor for interleukin-2.,online information:IL2RA mutation db,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta chain), and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain.,

leukocyte homeostasis, lymphocyte homeostasis, inflammatory response to antigenic stimulus, negative regulation of immune system process, positive regulation of immune system process, regulation of leukocyte activation, negative regulation of leukocyte activation, positive regulation of leukocyte activation, apoptosis, activation-induced cell death of T cells, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, cell death, cell proliferation, positive regulation of cell proliferation, negative regulation of cell proliferation, response to wounding, regulation of cell death, positive regulation of cell death, programmed cell death,death, negative regulation of defense response, regulation of response to external stimulus, negative regulation of response to external stimulus, regulation of homeostatic process, regulation of mononuclear cell proliferation,negative regulation of mononuclear cell proliferation, positive regulation of mononuclear cell proliferation, positive regulation of T cell proliferation, positive regulation of activated T cell proliferation, regulation of cell proliferation,regulation of T cell proliferation, negative regulation of T cell proliferation, homeostatic process, regulation of apoptosis, T cell homeostasis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, regulation of T cell differentiation, positive regulation of T cell differentiation,positive regulation of cell differentiation, regulation of lymphocyte differentiation, positive regulation of lymphocyte differentiation, regulation of activated T cell proliferation, regulation of T cell homeostatic proliferation, negative regulation of response to stimulus, homeostasis of number of cells, regulation of lymphocyte proliferation, positive regulation of lymphocyte proliferation, negative regulation of lymphocyte proliferation, regulation of inflammatory response, negative regulation of inflammatory response, regulation of T cell activation, regulation of cell activation,negative regulation of cell activation, positive regulation of cell activation, negative regulation of T cell activation,positive regulation of T cell activation, positive regulation of developmental process, regulation of lymphocyte activation, negative regulation of lymphocyte activation, positive regulation of lymphocyte activation, lymphocyte apoptosis, T cell apoptosis, regulation of leukocyte proliferation, negative regulation of leukocyte proliferation, positive regulation of leukocyte proliferation,

Membrane; Single-pass type I membrane protein.