HRH1

Histamine H1 receptor ;
H1R ;
HH1R ;

function:In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.,PTM:Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.,similarity:Belongs to the G-protein coupled receptor 1 family.,

defense response, inflammatory response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger, activation of phospholipase C activity, intracellular signaling cascade, cell-cell signaling, synaptic transmission, response to wounding, positive regulation of biosynthetic process, regulation of phospholipase activity, positive regulation of phospholipase activity, positive regulation of phospholipase C activity,transmission of nerve impulse, second-messenger-mediated signaling, positive regulation of cellular biosynthetic process, positive regulation of catalytic activity, positive regulation of molecular function, regulation of nitric oxide biosynthetic process, positive regulation of nitric oxide biosynthetic process, phosphoinositide-mediated signaling,neurological system process, positive regulation of nitrogen compound metabolic process, regulation of hydrolase activity, positive regulation of hydrolase activity, regulation of lipase activity, positive regulation of lipase activity,

Cell membrane ; Multi-pass membrane protein .