GATA6

Transcription factor GATA-6 ;
GATA-binding factor 6 ;

function:Thought to be important for regulating terminal differentiation and/or proliferation.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Expressed in heart, gut and gut-derived tissues.,

in utero embryonic development, liver development, transcription, regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter, phospholipid metabolic process, apoptosis, endoderm development, heart development, muscle organ development, cell death, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, regulation of specific transcription from RNA polymerase II promoter, positive regulation of specific transcription from RNA polymerase II promoter, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, programmed cell death, striated muscle tissue development, death, organophosphate metabolic process, respiratory tube development, lung development, epithelial cell differentiation, positive regulation of cellular biosynthetic process, regulation of gene-specific transcription, cardiac cell differentiation, tube development, muscle cell differentiation, chordate embryonic development, positive regulation of gene-specific transcription, regulation of transcription, positive regulation of cell differentiation, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, cardiac muscle tissue development,positive regulation of developmental process, striated muscle cell differentiation, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process,regulation of cardioblast differentiation, positive regulation of cardioblast differentiation, cardiac muscle cell differentiation, lung epithelium development, epithelium development, lung saccule development, lung cell differentiation, Clara cell differentiation, lung epithelial cell differentiation, Type II pneumocyte differentiation, muscle tissue development, respiratory system development,

Nucleus .

Expressed in heart, gut and gut-derived tissues. Expressed in skin upper pilosebaceous unit. Expression is decreased or lost in acne lesions (PubMed:33082341).