Total DAPP1 Cell-Based Colorimetric ELISA Kit
-KA4070C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
Primary Antibodies
BAM32 Rabbit pAb
YT0450
预览→
Primary Antibodies
BAM32 (Phospho Tyr139) Rabbit pAb
YP0549
预览→
ELISA Kits
Total DAPP1 Cell-Based Colorimetric ELISA Kit
KA4070C
预览→
ELISA Kits
DAPP1 (Phospho Tyr139) Cell-Based Colorimetric ELISA Kit
KA1449C
预览→
抗原&靶点信息
基因名称:
DAPP1
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别名:
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide ;
hDAPP1 ;
B lymphocyte adapter protein Bam32 ;
B-cell adapter molecule of 32 kDa ;
hDAPP1 ;
B lymphocyte adapter protein Bam32 ;
B-cell adapter molecule of 32 kDa ;
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背景:
function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
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功能:
protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process,dephosphorylation,
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细胞定位:
Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
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组织表达:
Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
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