Total B-Myb Cell-Based Colorimetric ELISA Kit
-KA4014C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
相关产品
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ELISA Kits
Total B-Myb Cell-Based Colorimetric ELISA Kit
KA4014C
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抗原&靶点信息
基因名称:
MYBL2
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别名:
Myb-related protein B ;
B-Myb ;
Myb-like protein 2 ;
B-Myb ;
Myb-like protein 2 ;
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背景:
function:Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.,PTM:Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22.,
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功能:
transcription, regulation of transcription,
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细胞定位:
Nucleus.
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