Total ATF3 Cell-Based Colorimetric ELISA Kit
-KA4001C
主要信息
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
ATF3
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别名:
Cyclic AMP-dependent transcription factor ATF-3 ;
cAMP-dependent transcription factor ATF-3 ;
Activating transcription factor 3 ;
cAMP-dependent transcription factor ATF-3 ;
Activating transcription factor 3 ;
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背景:
function:This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a homodimer or a heterodimer.,
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功能:
monosaccharide metabolic process, glucose metabolic process, pyruvate metabolic process, gluconeogenesis,transcription, regulation of transcription, DNA-dependent, positive regulation of cell proliferation, carbohydrate biosynthetic process, hexose metabolic process, hexose biosynthetic process, cellular carbohydrate biosynthetic process, regulation of cell proliferation, regulation of transcription, alcohol biosynthetic process, monosaccharide biosynthetic process, regulation of RNA metabolic process,
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细胞定位:
Nucleus .
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