CTSA

Lysosomal protective protein ;
Carboxypeptidase C ;
Carboxypeptidase L ;
Cathepsin A ;
Protective protein cathepsin A ;
PPCA ;
Protective protein for beta-galactosidase ;
[Cleaved into: Lysosomal protective protein 32 kDa chain ;
Lysosomal protective protein 20 kDa chain]

catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,

proteolysis, intracellular protein transport, protein localization, protein transport, cellular protein localization,establishment of protein localization, intracellular transport, cellular macromolecule localization,

Lysosome.