Cleaved Aggrecan (Asp369) Cell-Based Colorimetric ELISA Kit
-KA3916C
主要信息
Target
Aggrecan core protein
Reactivity
Human, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
ACAN AGC1 CSPG1 MSK16
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蛋白名称:
Aggrecan core protein
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别名:
Aggrecan core protein ;
Cartilage-specific proteoglycan core protein ;
CSPCP ;
Chondroitin sulfate proteoglycan core protein 1 ;
Chondroitin sulfate proteoglycan 1 ;
[Cleaved into: Aggrecan core protein 2]
Cartilage-specific proteoglycan core protein ;
CSPCP ;
Chondroitin sulfate proteoglycan core protein 1 ;
Chondroitin sulfate proteoglycan 1 ;
[Cleaved into: Aggrecan core protein 2]
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背景:
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008],
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功能:
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.
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细胞定位:
Secreted, extracellular space, extracellular matrix .
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组织表达:
Restricted to cartilages.
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