Total CYP39A1 Cell-Based Colorimetric ELISA Kit
-KA3898C
主要信息
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
详细信息
储存
2-8°C/6 months
修饰
Unmodified
检测方法
Colorimetric
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抗原&靶点信息
基因名称:
CYP39A1
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别名:
24-hydroxycholesterol 7-alpha-hydroxylase ;
Cytochrome P450 39A1 ;
hCYP39A1 ;
Oxysterol 7-alpha-hydroxylase ;
Cytochrome P450 39A1 ;
hCYP39A1 ;
Oxysterol 7-alpha-hydroxylase ;
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背景:
catalytic activity:(24R)-cholest-5-ene-3-beta,24-diol + NADPH + O(2) = (24R)-cholest-5-ene-3-beta,7-alpha,24-triol + NADP(+) + H(2)O.,cofactor:Heme group.,function:Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver specific.,
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功能:
steroid biosynthetic process, bile acid biosynthetic process, steroid catabolic process, cholesterol catabolic process,digestion, steroid metabolic process, cholesterol metabolic process, bile acid metabolic process, lipid biosynthetic process, lipid catabolic process, organic acid biosynthetic process, organic acid catabolic process, sterol metabolic process, sterol catabolic process, bile acid catabolic process, carboxylic acid biosynthetic process, carboxylic acid catabolic process, oxidation reduction,
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细胞定位:
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .
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组织表达:
Liver specific.
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