TRERF1

Transcriptional-regulating factor 1 ;
Breast cancer anti-estrogen resistance 2 ;
Transcriptional-regulating protein 132 ;
Zinc finger protein rapa ;
Zinc finger transcription factor TReP-132 ;

function:Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.,similarity:Contains 1 ELM2 domain.,similarity:Contains 1 SANT domain.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with CREBBP and EP300.,tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.,

transcription, regulation of transcription, DNA-dependent, steroid biosynthetic process, steroid catabolic process,cholesterol catabolic process, steroid metabolic process, cholesterol metabolic process, lipid biosynthetic process,positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, lipid catabolic process, sterol metabolic process, sterol catabolic process, positive regulation of cellular biosynthetic process, regulation of hormone metabolic process, homeostatic process, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, regulation of hormone biosynthetic process, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process,

Nucleus .

Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells.